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2021 | 2 |
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Fosdenopterin: First Approval.
Drugs. 2021 Jun;81(8):953-956. doi: 10.1007/s40265-021-01520-2.
Drugs. 2021.
PMID: 33909276
Review.
Fosdenopterin (Nulibry(TM)) is a synthetic cyclic pyranopterin monophosphate that is being developed by Origin Biosciences (a subsidiary of BridgeBio Pharma) for the treatment of molybdenum cofactor deficiency (MoCD) type A. ...This article summarizes the milestones …
Fosdenopterin (Nulibry(TM)) is a synthetic cyclic pyranopterin monophosphate that is being developed by Origin Biosciences (a …
Regulatory news: Nulibry (fosdenopterin) approved to reduce the risk of mortality in patients with molybdenum cofactor deficiency type A: FDA approval summary.
Farrell S, Karp J, Hager R, Wang Y, Adeniyi O, Wang J, Li L, Ma L, Peretz J, Summan M, Kong N, White M, Pacanowski M, Price D, Filie J, Donohue K, Joffe H.
Farrell S, et al.
J Inherit Metab Dis. 2021 Sep;44(5):1085-1087. doi: 10.1002/jimd.12421. Epub 2021 Aug 8.
J Inherit Metab Dis. 2021.
PMID: 34337775
Review.
No abstract available.
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S-sulfocysteine/NMDA receptor-dependent signaling underlies neurodegeneration in molybdenum cofactor deficiency.
Kumar A, Dejanovic B, Hetsch F, Semtner M, Fusca D, Arjune S, Santamaria-Araujo JA, Winkelmann A, Ayton S, Bush AI, Kloppenburg P, Meier JC, Schwarz G, Belaidi AA.
Kumar A, et al.
J Clin Invest. 2017 Dec 1;127(12):4365-4378. doi: 10.1172/JCI89885. Epub 2017 Nov 6.
J Clin Invest. 2017.
PMID: 29106383
Free PMC article.
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